Lipotropic Actions of Methyl Methionine Sulfonium Chloride, Homocysteine Thiolactone and L-Methionine on Cholesterol Fatty Liver in Rabbits
نویسندگان
چکیده
منابع مشابه
The preparation of [35S]homocysteine thiolactone free of [35S]methionine.
The unambiguous study of homocysteine metabolism requires a source of [355]homocysteine completely free from contaminating [35S]methionine. Until now, such a reagent has not been readily available. Homocysteine is an important metabolite involved in methionine, cysteine and methylation metabolism. Homocysteine can be methylated to form methionine with either 5-methyltetrahydrofolate [1] or beta...
متن کاملMethionine, DL-homocysteine thiolactone and n-acetyl-DL-methionine for ruminants.
Plasma amino acid response of wethers to abomasal infusions of DL-methionine (DLM), DL-homocysteine thiolactone-HCl (HCTL) and N-acetyl-DL-methionine (NAM), in vivo rumen stability of the latter two methionine analogs and preintestinal absorption of HCTL were studied. The daily infusion of 1.06 g of DLM elevated molar percentage of methionine and lysine in plasma'and decreased molar percentage ...
متن کاملTumor uptake studies of S-adenosyl-L-[methyl-11C]methionine and L-[methyl-11C]methionine.
Tumor accumulation of S-adenosyl-L-[methyl-11C]methionine ([11C]SAM) was investigated in mice bearing mammary carcinoma (FM3A) and in rats bearing ascitic hepatoma (AH109A). After injection of [11C]SAM the blood clearance of 11C radioactivity was rapid. The 11C level was relatively high in both tumors. The uptake ratios of tumor to organ increased with time in several organs, especially in brai...
متن کاملLipotropic factors and the fatty liver produced by feeding cholesterol.
The excessive deposition of liver lipids which is produced in rats by feeding diets containing cholesterol is inhibited by choline and betaine (Best & Ridout, 1933; Best, Channon & Ridout, 1934). Choline was shown to affect both glycerides and cholesteryl esters but deposition of the former was inhibited more than that of the latter. .Many preventive and curative experiments were subsequently r...
متن کاملDysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease
Methionine metabolism plays a central role in methylation reactions, production of glutathione and methylarginines, and modulating homocysteine levels. The mechanisms by which these are affected in NAFLD are not fully understood. The aim is to perform a metabolomic, molecular and epigenetic analyses of hepatic methionine metabolism in diet-induced NAFLD. Female 129S1/SvlmJ;C57Bl/6J mice were fe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Kansai Medical University
سال: 1963
ISSN: 0022-8400
DOI: 10.5361/jkmu1956.15.1_58